Beilstein J. Org. Chem.2013,9, 641–646, doi:10.3762/bjoc.9.72
analytical methods. Using NMR we show that GHB glucuronide 2 is highly stable towards aqueous hydrolysis within the pH range normally observed for urine even at elevated temperature.
Keywords: analytical chemistry; cabohydratechemistry; forensic chemistry; glucuronide; γ-hydroxybutyric acid; metabolite
PDF
Graphical Abstract
Figure 1:
Hypothesised glucuronidation of GHB (1) by UDP-glucuronosyltransferase to give glucuronide 2. UDP =...